Properties:
| Appearance & Physical State | White to slightly yellow crystalline powder. |
|---|---|
| Density | 1.45 g/cm3 |
| Boiling Point | 405.4ºC at 760 mmHg |
| Melting Point | 159-163ºC |
| Flash Point | 199ºC |
| Refractive Index | 1.612 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Storage Condition | 2-8ºC |
| Vapor Pressure | 2.67E-07mmHg at 25°C |
Metronidazole is an antibiotic that is used commonly to treat protozoal infections and anaerobic bacterial infections. It also has anti-inflammatory effects in the bowel. Metronidazole is bactericidal; it kills bacterial microorganisms by disrupting their DNA. It is absorbed rapidly from the GI tract, metabolized by the liver and excreted in the urine and the feces. Because metronidazole only has activity against anaerobic bacteria, it is used commonly with other antibiotics when it is used to treat mixed-bacterial infections. It is compatible with many other antibiotics including penicillin antibiotics, aminoglycosides, and some cephalosporins.
Metronidazole is used in the treatment of intestinal and parenteral amoeba disease (such as amoeba liver abscess, pleural amoeba disease, etc.).Also can be used to treat vaginal trichomoniasis, bagworm disease and cutaneous leishmaniasis, guinea worm infection.It is also widely used in the treatment of anaerobe infection.