vitamin b6 injection
Indications
1. Suitable for the prevention and treatment of vitamin B6 deficiency, prevention and treatment of isoniazid poisoning; can also be used for vomiting caused by pregnancy, radiation sickness and anticancer drugs, seborrheic dermatitis, etc.
2. Vitamin B6 supplementation during total parenteral nutrition and malnutrition caused by insufficient intake and progressive weight loss.
3. The following situations increase the need for vitamin B6: pregnancy and lactation, hyperthyroidism, burns, long-term chronic infection, fever, congenital metabolic disorders, intestinal diseases , and post-gastrectomy.
4. Neonatal hereditary vitamin B6 dependence syndrome.
Dosage and Administration
Usage: Subcutaneous injection, intramuscular injection or intravenous injection.
Dosage:
50mg-100mg once a day. When used for the detoxification of cycloserine poisoning, 300mg or more per day. When used for the detoxification of isoniazid poisoning, 1g of vitamin B6 is given intravenously for every 1g of isoniazid.
Precautions & Warning:
1.Vitamin B6 has not been proven to be effective in the following conditions, such as acne and other skin diseases, alcoholism, asthma, kidney stones, mental illness, migraine, premenstrual tension, stimulation of milk secretion, and loss of appetite. It is not advisable to use large doses of vitamin B6 to treat diseases that have not been proven to be effective.
2. Vitamin B6 affects the efficacy of levodopa in the treatment of Parkinson's disease, but has no effect on the efficacy of carbidopa.
3. Interference with diagnosis: false positive in urobilinogen test.
Contraindications:
Not yet clear
Adverse Reactions:
1.Vitamin B6 is almost non-toxic when renal function is normal. Allergic reactions are rare. If 200 mg is used daily for more than 30 days, it may cause dependence syndrome.
Drug interactions:
1 Chloramphenicol, cycloserine, ethionamide, hydralazine hydrochloride, immunosuppressants including adrenocortical hormones, cyclophosphamide, cyclosporine, isoniazid, penicillamine and other drugs can antagonize vitamin B6 or increase the renal excretion of vitamin B6, which can cause anemia or peripheral neuritis.
2 The dosage of vitamin B6 should be increased when taking estrogen.
3 Levodopa combined with a small dose of vitamin B6 (5 mg per day) can antagonize the anti-tremor effect of levodopa.
Storage instructions:
Keep away from light and store in a sealed container