chlorphenamine maleate tablet
Indications:
Chlorphenamine tablets are indicated for symptomatic control of all allergic conditions responsive to antihistamines including hay fever, vasomotor rhinitis, urticaria, angioneurotic oedema, food allergy, drug and serum reactions and insect bites.
Also indicated for the symptomatic relief of itch associated with chickenpox.
Dosage and Administration:
Usage: Oral use.
Dosage:
1 tablet (4mg) every 4 to 6 hourly.
Maximum daily dose: 6 tablets (24mg) in any 24 hours.
Elderly:
The elderly are more likely to experience neurological anticholinergic effects. Consideration should be given to using a lower daily dose (e.g. a maximum of 12 mg in any 24 hours).
Children aged 6 - 12 years:
½ tablet (2mg) 4 to 6 hourly.
Maximum daily dose: 3 tablets (12mg) in any 24 hours.
Not recommended for children under the age of 6 years.
Precautions & Warning:
1.Chlorphenamine in common with other drugs having anticholinergic effects, should be used with caution in epilepsy, raised intra-ocular pressure including glaucoma, prostatic hypertrophy; severe hypertension or cardiovascular disease; bronchitis, bronchiectasis and asthma; hepatic impairment; renal impairment. Children and the elderly are more likely to experience the neurological anticholinergic effects and paradoxical excitation (e.g. increased energy, restlessness, nervousness). Avoid use in elderly patients with confusion.
2.The anticholinergic properties of chlorphenamine may cause drowsiness, dizziness, blurred vision and psychomotor impairment in some patients which may seriously affect ability to drive and use machinery.
3.Concurrent use with drugs which cause sedation such as anxiolytics and hypnotics may cause an increase in sedative effects, therefore medical advice should be sought before taking chlorphenamine concurrently with these medicines.
4.The effects of alcohol may be increased and therefore concurrent use should be avoided.
Should not be used with other antihistamine containing products, including antihistamine containing cough and cold medicines
5.Patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsorption should not take this medicine. Keep out of the sight and reach of children.
Contraindications:
1.Hypersensitivity to the active substance or to any of the excipients。
2.The anticholinergic properties of chlorphenamine are intensified by monoamine oxidase inhibitors (MAOIs). The tablets are therefore contraindicated in patients who have been treated with MAOIs within the last fourteen days.
Adverse Reactions
1.Nervous system disorders: Sedation, somnolence; Disturbance in attention, abnormal co-ordination, dizziness, headache
2.Eye disorders: Blurred vision
3.Gastrointestinal disorders: Nausea, dry mouth
4.General disorders and administration site conditions: Fatigue
Storage instructions:
Do not store above 25°C and store in the original container.