Dexamethasone Sodium Phosphate Injection 8mg/2ml
DEXAMETHASONE SODIUM PHOSPHATE INJECTION 8MG/2ML
Indications:
Dexamethasone Solution for Injection is indicated in acute conditions in which oral glucocorticoid therapy is not feasible such as:
Shock: of haemorrhagic, traumatic, surgical or septic origin; cerebral oedema associated with cerebral neoplasm; inflammatory diseases of joints and soft tissue such as rheumatoid arthritis.
Short term management of acute self-limited allergic conditions such as angioneurotic oedema or acute exacerbations of chronic allergic disorders such as bronchial asthma or serum sickness.
Dosage and Administration:
Dexamethasone sodium phosphate injection may be administered by intramuscular, intraarticular or direct intravenous injection, intravenous infusion or soft tissue infiltration.
Intravenous and Intramuscular Administration: IM or IV dosage of dexamethasone is variable, depending on the condition being treated. It usually ranges from 0.4 to 20 mg (0.1 to 6 ml) daily. The duration of therapy is dependent on the clinical response of the patient and as soon as improvement is indicated, the dosage should be adjusted to the minimum required to maintain the desired clinical response. Withdrawal of the drug on completion of therapy should be gradual.
Precautions & Warning:
Dexamethasone withdrawal
Visual disturbance
Hypertrophic cardiomyopathy(In paediatric population)
Contra-indications:
Unless considered to be life-saving systemic administration of corticosteroids are generally contraindicated in patients with systemic infections, (unless specific anti-infective therapy is employed).
Hypersensitivity to any components of the injection.
Drug interactions:
Liver enzyme inducing drugs
Coumarin anticoagulants
Anti-inflammatory drugs
Salicylate
Diuretics
Co-treatment with CYP3A inhibitors
Storage instructions:
Do not store above 25°C. Do not freeze. Keep container in the outer carton.