5% glucose and 0.9% sodium chloride injection
Indications
1. Fluid And Electrolyte Substitution In Hypochloremic Alkalosis
2. Chloride Losses
3. Hypotonic Dehydration
4. Isotonic Dehydration
5. Partial Coverage Of Energy Requirements
6. Vehicle Solution For Compatible Electrolyte Concentrates And Medicaments
Dosage and Administration
Usage: Intravenous use.
Dosage:
The dose is adjusted according to the individual requirements of fluid, electrolyte and energy. thus the patient`s age, weight, clinical and biological (acid-base balance) conditions and concomitant therapy should be taken into account.
Precautions & Warning:
1.5% glucose and 0.9% sodium chloride injection should only be administered with caution in cases of hypernatraemia, hyperchloraemia and disorders where restriction of sodium intake is indicated, such as cardiac insufficiency, generalized oedema, pulmonary oedema, hypertension, eclampsia, severe renal insufficiency.
2. In patients with acute ischaemic stroke and hyperglycaemia the glucose level should be corrected before application of this solution.
3. In diabetic patients, the amount of infused glucose has to be taken into account and insulin requirements may be modified.
4. To prevent development of the osmotic demyelination syndrome in patients with chronic hyponatraemia the rate of administration should be sufficiently low, so that the serum sodium will not increase faster than by 0.35 - 0.5 mmol/h corresponding to 8 - 12 mmol/l/d.
5. Please note: If this solution is used as vehicle solution the safety information of the additive provided by the respective manufacturer have to be taken into account.
Clinical monitoring should include checks of the serum electrolytes (especially potassium), glucose level, the acid-base and water balance.
6.In post-operative and post-traumatic conditions, and in conditions of impaired glucose tolerance: only administer with monitoring of blood glucose level.
7.The solution should not be administered through the same infusion equipment simultaneously, before or after an administration of blood because of the possibility of pseudo-agglutination.
8.In case of an adverse reaction, infusion must be stopped immediately.
Contraindications:
1.Hyperhydration
2.Hypertonic Dehydration
3.Untreated Hypokalaemia
4.Metabolic Acidosis
5.Persistent Hyperglycaemia not responding to insulin doses of up to 6 units/hour
6.Pulmonary Or Brain Oedema
7.Decompensated Cardiac Insufficiency
Adverse Reactions:
1.Adverse reactions may be associated to the technique of administration including febrile response, infection at the site of injection, local pain or reaction, vein irritation, venous thrombosis or phlebitis.
2.Adverse reactions may be associated with the medications added to the solution; the nature of the additive will determine the likelihood of any other undesirable effects.
Storage instructions:
This medicinal product does not require any special storage conditions